Takemichi Hanagaki is a freelancer that’s reached the absolute pits of despair in his life. He finds out that the only girlfriend he ever had, in middle school, Hinata Tachibana, had been killed by the ruthless Tokyo Manji Gang. The day after hearing about her death, he’s standing on the station platform and ends up being pushed over onto the tracks by a herd of people. He closes his eyes thinking he’s about to die, but when he opens his eyes back up, he somehow had gone back in time 12 years. Now that he’s back living the best days of his life, Takemichi decides to get revenge on his life.
Two transfer students, Atsuko Maeda and Onizuka Daruma came at the all-girls school Majisuka Gakuen. In this school violence and fighting are common among the Yankee students. Noisy and trouble maker Daruma made a fuss as soon as she entered the school, win in her first fight but then was beaten easily by another gang shortly after. In contrary to Daruma's bold-but-powerless attitude, Maeda who is truthfully a strong girl despite of her silent nature found Daruma is beaten by Team Hormon before her. The word "Majisuka?" (means are you serious?) instantly awaken her true nature and made her won the battle against Daruma's attackers easily, thus made a big fuss at the school and the news even reached the strongest fighting group, Rappapa. Afterwards, Daruma acknowledged Maeda as her boss and as a result the friendship between the two girls began to grow along with their fights with fellow students at their school.